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▐███▓█▄▄ ░ ▐████▓▓░ ▐██▓▓ │Love may be blind, but │ ░ ▄▄█▓███▌
██▀▀▀██▓▓▄ ███▓▓ ██▓▓▌ │marriage is a real eye-opener.│ ▄▓▓██▀▀▀██
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▀███▓███▓▀▀ ■■ The diGERATi Present ■■ ▀▀▓███▓███▀
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█▄▄▄▄▄ Lipid_Data_Analyzer_v1.5.2_Incl_Keygen-DIGERATI ▄▄▄▄▄▄█
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▐██▓▓ ■ ■ ███▓▌
███▀ ■■ Release Info ■■ ▀██▓
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▐█▓▓ Cracker ......: DIGERATI Release-Type..: Incl_Keygen ██▓▌
██▓▌ Packager......: DIGPACKER Release-Date..: 6/22/2011 ▐██▓
██▓ Supplier......: DIGERATI Protection....: Time Limit ██▓
▐██ Coder.........: DIGERATI OS............: WinALL █▓▌
██▓ ░ Company.......: Files.........: xx/07 ░▓█▓
▀██░ ░█▓▀
▀██░ URL: http://genome.tugraz.at/lda ░█▓▀
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█▄ █▄▀▀████▓▀ ▐█▓▌ ▀ ■■ Release Notes ■■ ▀ ▐█▓▌ ▀▓████▀▀▄█ ▄█
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██▓ The accurate measurement of the lipidome permits insights ██▓
██▓ into physiological and pathological processes. Of the ██▓
██▓ present high-throughput technologies, LC-MS especially ██▓
██▓ bears potential of monitoring quantitative changes in ██▓
██▓ hundreds of lipids simultaneously. In order to extract ██▓
██▓ valuable information from huge amount of mass spectrometry ██▓
██▓ data, the aid of automated, reliable highly sensitive and ██▓
██▓ specific analysis algorithms is indispensable. ██▓
██▓ ██▓
██▓ We present here a novel approach for the quantitation of ██▓
██▓ LC-MS data. The new algorithm obtains its analytical power ██▓
██▓ by two major innovations: 1) a 3D algorithm that confines ██▓
██▓ the peak borders in m/z and time direction and 2) the use ██▓
██▓ of the theoretical isotopic distribution of an analyte as ██▓
██▓ selection/exclusion criterion. The algorithm is integrated ██▓
██▓ in the Lipid Data Analyzer (LDA) application, which ██▓
██▓ additionally provides standardisation, a statistics module ██▓
██▓ for results analysis, a batch mode for unattended analysis ██▓
██▓ of several runs and a 3D viewer for the manual ██▓
██▓ verification. ██▓
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██▓ The statistics module offers sample grouping, tests ██▓
██▓ between sample groups and export functionalities, where ██▓
██▓ the results are visualised by heat maps and bar charts. ██▓
██▓ The presented algorithm has been applied to data from a ██▓
██▓ controlled experiment and to biological data, containing ██▓
██▓ analytes distributed over an intensity range of 10^6. Our ██▓
██▓ approach shows improved sensitivity and an extremely high ██▓
██▓ positive predictive value compared to existing methods. ██▓
██▓ Consequently, this application is a valuable improvement ██▓
██▓ in the high-throughput analysis of lipids. ██▓
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██▓ ░ ▄ ▀▀▄ ■ ■ ▄▀▀ ▄ ░ ▓█▓
▀██▓▄▄ ▐██▄ ▄ ■■ Install Notes ■■ ▄ ▄█▓▌ ▄▄▓██▀
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█▓ █▓▀ ▀▓█ █▓
█▓▌▀█ 1. Unpack and install the software █▀▐█▓
█▓▌▀█ 2. Run keygen.html to create your own serial -or- if you're █▀▐█▓
█▓▌▀█ lazy, use info in serial.txt █▀▐█▓
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▐█▓▌ ▄██▄ ▄▄█▓▄▄ ▄▄▀▀■ ■▀▀▄▄ ▄▄██▓▄ ▄██▄ ▐█▓▌
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▄▄▄▄█ ■■ Mission Statement: ■■ █▄▄▄▄
▄█▓ █▓▌ A few years ago, DiGERATi emerged onto the scene. ▐█▓ █▓▄
█▓▌ ▐█▓ Focusing on quality rather than quantity, our █▓▌ ▐█▓
▀█▓ █▓▌ members have successfully tackled some of the toughest ▐█▓ █▓▀
▀▀▄ █▓▌ challenges in the scene. Working as a closely unified ▐█▓▄▀▀
▐█▓ team we have maintained some of the highest standards ██▓
██▓██ for security, quality, innovation, and comradery in the ██ ██▓
▐█▓ ▐█ scene today. DiGERATi is not one or two hardworking ▓▌ █▓▌
█▓ █▓ persons; it is a force of hardworking people. Respect ██▓ █▓
█▓ █▓▓ is not to be demanded; it is to be earned! We look ██▓ █▓
▄█▓ ▄█▓▓ forward to working even harder in the future to continue ██▓▄ █▓▄
▐█▓▌ ██▓▓ & to earn the respect of our peers. For anyone other than ██▓▓ ▐█▓▌
▐██▓ ██▓▀ our peers, WE DO NOT EXIST! ▀██▓██▓▓
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▀█▄ ▐██▓▓▓▌ ░ ░ █ █ ▀ █▀▀ ▓▀▄ ▄▀▀ ▀█ █▄▄ █ ░ ░ ▐███▓▓▌ ▄█▀
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▐▓▌ ■■ Our Respect goes out to: ■■ ▓▌
▐▓▌ ▓▌
▀█▄▄ BliZZARD BRD CORE CRD DELIGHT DVT DDU EAT F4CG EMBRACE ▄█▀
▄▄▄▄█ HAZE HERETIC LZ0 SHOCK SSG TBE UNDERPL ZWT █▄▄▄▄
▄▄▄▄█ █▄▄▄▄
▄█▓ █▓▌ ■ Greets to all who work hard help make the scene secure! ▐█▓ █▓▄
▄█▓ █▓▌ ▐█▓ █▓▄
█▓▌ ▐█▓ ■ A special thanks to those who supported us in the past and █▓▌ ▐█▓
▀█▓ █▓▌ helped to make us what we are today.Also,a major thanks to ▐█▓ █▓▀
▀▀▄ █▓▌ those that broke the trail for us but can no longer be ▐█▓ ▄▀▀
▐█▓ here amongst us. █▓▌
██▓ █ ███▓
▐█▓ ▐█ ■ Who are the "digerati" and why are they "the cyber elite"? ▓ █▓▌
█▓ █▓ They are the doers and thinkers. They are not on the ██▓ █▓
█▓ █▓▓ frontier, they are the frontier!!... ██▓ █▓
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▐▓▌ Yce ▐▓▌
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